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The Wallenberg Neuroscience Center (WNC) was established in 1996 as a joint venture between Lund University and Skåne University Hospital. The WNC building was partly funded by a major grant from the Knut and Alice Wallenberg Foundation as…

https://www.wnc.lu.se/about-us- 2021-03-17

A revolution in the study of monoamine systems in the CNS Long before the modern era of selective and sensitive antibodies that have allowed virtually any protein of choice to be visualized immunohistochemically, the monoamine…

https://www.wnc.lu.se/about-us/falck-hillarp-method- 2023-01-09

Scientists in Lund have pioneered the use of fetal dopamine neurons for transplantation in Parkinson´s Disease. This approach was developed from 1979-1983 in a series of animal experimental studies (publications 1 below), followed by more…

https://www.wnc.lu.se/cell-therapy-parkinsons-disease- 2021-02-23

    We are located in the Biomedical Center (BMC) in Lund in the south of Sweden.  Our visiting address is Sölvegatan 17. How to get to Lund From Copenhagen airport:  Copenhagen airport Kastrup (CPH) is Denmark's international airport, and…

https://www.wnc.lu.se/about-us/visit-us- 2021-03-11

https://www.wnc.lu.se/sites/wnc.lu.se/files/1-s2.0-s2211124712001222-main.pdf

Microsoft Word - Acta3.doc

https://www.wnc.lu.se/sites/wnc.lu.se/files/acta_physiol_scand_suppl._522_19-28_1983.pdf

PII: 0006-8993(79)90472-4 Bram Research, 177 (1979) 555 560 555 c(', Elsevier/North-Holland B~omedical Press Reconstruction of the nigrostriatal dopamine pathway by intracerebral nigral transplants ANDERS BJORKLUND and ULF STENEVI Depal…

https://www.wnc.lu.se/sites/wnc.lu.se/files/bjorklund_stenevi_brain_res_1979.pdf

Behavioural effects of human fetal dopamine neurons grafted in a rat model of Parkinson's disease Exp Brain Res (1986) 65:235-240 Experimental Brain Research 9 Springer-Verlag 1986 Research Note Behavioural effects of human fetal dopamine…

https://www.wnc.lu.se/sites/wnc.lu.se/files/brundin_et_al_exp_brain_res_1986.pdf

Human fetal dopamine neurons grafted in a rat model of Parkinson's disease: immunological aspects, spontaneous and drug-induced behaviour, and dopamine release Exp Brain Res (1988) 70:192-208 Experimental Brain Research 9 Springer-Verlag…

https://www.wnc.lu.se/sites/wnc.lu.se/files/brundin_et_al_exp_brain_res_1988.pdf

Human fetal dopamine neurons grafted in a rat model of Parkinson's disease: ultrastructural evidence for synapse formation using tyrosine hydroxylase immunocytochemistry Exp Brain Res (1988) 73:115-126 E ,x _'mental Bran Research 9…

https://www.wnc.lu.se/sites/wnc.lu.se/files/clarke_et_al_exp_brain_res_1988.pdf

PII: 0006-8993(81)91007-6 Brain Research, 229 (1981) 457-470 457 Elsevier/North-Holland Biomedical Press B E H A V I O U R A L RECOVERY F O L L O W I N G T R A N S P L A N T A T I O N OF SUBS- T A N T I A N I G R A IN RATS SUBJECTED TO 6…

https://www.wnc.lu.se/sites/wnc.lu.se/files/dunnett_et_al_part_ii_brain_res_1981.pdf

Since the fusions are intraspecies, and in many cases involve highly aneuploid lines, it is not possible to perform de- tailed cytogenetic analyses. However, comparisons of total chromosome counts of hybrid clones with those of the…

https://www.wnc.lu.se/sites/wnc.lu.se/files/gage_et_al_science_1983.pdf

Brain (1999),122,1121–1132 Sequential bilateral transplantation in Parkinson’s disease Effects of the second graft P. Hagell,1 A. Schrag,5 P. Piccini,7 M. Jahanshahi,6 R. Brown,6 S. Rehncrona,2 H. Widner,1,4 P. Brundin,4 J. C. Rothwell,6 P…

https://www.wnc.lu.se/sites/wnc.lu.se/files/hagell_et_al_brain_1999.pdf

C2MDS#090606 1..6 Brief Report Characterization of Lewy Body Pathology in 12- and 16-Year-Old Intrastriatal Mesencephalic Grafts Surviving in a Patient With Parkinson’s disease Jia-Yi Li, MD, PhD,1* Elisabet Englund, MD,2 Håkan Widner, MD…

https://www.wnc.lu.se/sites/wnc.lu.se/files/li_et_al_mvdis_2010.pdf

Cell Therapy in Parkinson’s Disease Olle Lindvall and Anders Bjo¨rklund Wallenberg Neuroscience Center and Lund Strategic Center for Stem Cell Biology and Cell Therapy, BMC A11, SE-221 84 Lund, Sweden Summary: The clinical studies with…

https://www.wnc.lu.se/sites/wnc.lu.se/files/lindvall_and_bjorklund_neurorx_2004.pdf

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https://www.wnc.lu.se/sites/wnc.lu.se/files/lindvall_et_al_ann_neurology_1992.pdf

Grafts of Fetal Dopamine Neurons Survive and Improve Motor Function in Parkinson's Disease Article Contents p.574 p.575 p.576 p.577 Issue Table of Contents Science, New Series, Vol. 247, No. 4942 (Feb. 2, 1990), pp. 505-604 Front Matter …

https://www.wnc.lu.se/sites/wnc.lu.se/files/lindvall_et_al_science_1990.pdf

Delayed recovery of movement-related cortical function in Parkinson's disease after striatal dopaminergic grafts Delayed Recovery of Movement-Related Cortical Function in Parkinson’s Disease after Striatal Dopaminergic Grafts Paola Piccini…

https://www.wnc.lu.se/sites/wnc.lu.se/files/piccini_et_al_ann_neurol_2000_0.pdf

Extensive graft-derived dopaminergic innervation is maintained 24 years after transplantation in the degenerating parkinsonian brain Extensive graft-derived dopaminergic innervation is maintained 24 years after transplantation in the…

https://www.wnc.lu.se/sites/wnc.lu.se/files/pnas-2016-li-1605245113.pdf

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https://www.wnc.lu.se/sites/wnc.lu.se/files/wenning_et_al_ann_neurology_1997_0.pdf